Article
Detection of residual disease in pediatric B-cell precursor acute lymphoblastic leukemia by comparative phenotype mapping: a study of five cases controlled by genetic methods.
Experimental hematology - 1 Apr 1999
Dworzak M N, Stolz F, Fröschl G, Printz D, Henn T, Fischer S, Fleischer C, Haas O A, Fritsch G, Gadner H, Panzer-Grümayer E R
Abstract excerpt
We recently investigated samples of pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL) and normal bone marrow (BM). We found that leukemic blasts, compared to their physiologic counterpart cells, frequently display aberrant phenotypes with respect to levels of expression of certain antigens. Using multiparameter flow cytometry, these differences enabled us to trace leukemic cells admixed to normal...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.