Article
Aberrant splicing of intron 1 creates a novel null HLA-B*1501 allele.
Tissue antigens - 1 Mar 1999
Curran M D, Williams F, Little A M, Rima B K, Madrigal J A, Middleton D
Abstract excerpt
A comparison of serological and DNA HLA class I typing data identified a serological "blank" HLA-B15 antigen in a volunteer donor on the bone marrow registry. Isoelectric focusing and Western blot analysis of a cell line established from this individual confirmed that the HLA-B15 antigen is not expressed at the cell surface. Nucleotide sequence analysis of the HLA-B*15 null allele revealed a 10-bp deletion near...
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