Article
[Ontogeny of the immune system].
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie - 1 Jan 1999
Millet V, Lacroze V, Bodiou A C, Dubus J C, D'Ercole C, Unal D
Abstract excerpt
The newborn immune system differs quantitatively and functionally from adults. At birth, the immune system is partially immature, resulting in deficiency in cell-mediated cytolysis, immunoglobulin synthesis and cytokine production. The most clearly defined deficit in neonatal phagocytosis defenses is diminished neutrophil storage. T cell function is diminished, including T cell-mediated cytotoxicity and T cell...
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