Article
Effects of insulin-like growth factor I treatment on statural growth, body composition and phenotype of children with growth hormone insensitivity syndrome. GHIS Collaborative Group.
Acta paediatrica (Oslo, Norway : 1992). Supplement - 1 Feb 1999
Underwood L E, Backeljauw P, Duncan V
Abstract excerpt
Eight children with growth hormone insensitivity syndrome (GHIS) have been treated with injections of recombinant human insulin-like growth factor I (rhIGF-I) for more than 5 years each. After good acceleration of growth in the first year of therapy, the growth rate decreased to an average of 5-6 cm/year. In general, growth with IGF-I therapy is less exuberant than that observed with growth hormone (GH) therapy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.