Article
Studies of human immunodeficiency virus type 1 mucosal viral shedding and transmission in Kenya.
The Journal of infectious diseases - 1 May 1999
Overbaugh J, Kreiss J, Poss M, Lewis P, Mostad S, John G, Nduati R, Mbori-Ngacha D, Martin H, Richardson B, Jackson S, Neilson J, Long E M, Panteleeff D, Welch M, Rakwar J, Jackson D, Chohan B, Lavreys L, Mandaliya K, Ndinya-Achola J, Bwayo J
Abstract excerpt
If human immunodeficiency virus type 1 (HIV-1) vaccines are to be highly effective, it is essential to understand the virologic factors that contribute to HIV-1 transmission. It is likely that transmission is determined, in part, by the genotype or phenotype (or both) of infectious virus present in the index case, which in turn will influence the quantity of virus that may be exchanged during sexual contact....
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