Article
Overexpression of eCLCA1 in small airways of horses with recurrent airway obstruction.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Aug 2005
Anton Friederike, Leverkoehne Ina, Mundhenk Lars, Thoreson Wallace B, Gruber Achim D
Abstract excerpt
The human hCLCA1 and murine mCLCA3 (chloride channels, calcium-activated) have recently been identified as promising therapeutic targets in asthma. Recurrent airway obstruction in horses is an important animal model of human asthma. Here, we have cloned and characterized the first equine CLCA fam...
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