Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cloning and expression of the human p8, a nuclear protein with mitogenic activity

1 Feb 1999

Abstract excerpt

We have previously identified a new rat mRNA, provisionally named p8, which showed a strong, but transient, induction in the pancreas in response to acute pancreatitis. We report here the cloning and sequencing of the human p8 cDNA. The human p8 polypeptide is 82 amino acids long and shows an overall identity of 74% with the rat counterpart. The complete structure of the p8 gene was also established. The p8 gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to Pancreatic and Hepatic Oncology Research
Share to Pancreatitis Pathology and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 10092851
DOI: 10.1046/j.1432-1327.1999.00092.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cloning and expression of the human p8, a nuclear protein with mitogenic activityPMID 10092851Read ↗

Cloning and Expression of the Rat p8 cDNA, a New Gene Activated in Pancreas during the Acute Phase of Pancreatitis, Pancreatic Development, and Regeneration, and Which Promotes Cellular GrowthSemantic proximity Read ↗

Molecular Cloning, Genomic Organization, and Chromosomal Localization of the Human Pancreatitis-Associated Protein (PAP) GeneSemantic proximity Read ↗

Molecular cloning and functional expression analysis of a cDNA for human hepassocin, a liver-specific protein with hepatocyte mitogenic activitySemantic proximity Read ↗

Human Pancreatic Islets Express mRNA Species Encoding Two Distinct Catalytically Active Isoforms of Group VI Phospholipase A2 (iPLA2) That Arise from an Exon-skipping Mechanism of Alternative Splicing of the Transcript from the iPLA2 Gene on Chromosome 22q13.1Semantic proximity Read ↗

p8 inhibits the growth of human pancreatic cancer cells and its expression is induced through pathways involved in growth inhibition and repressed by factors promoting cell growth.Semantic proximity Read ↗

Nuclear P38: Roles in Physiological and Pathological Processes and Regulation of Nuclear TranslocationSemantic proximity Read ↗

Cloning and Characterization of the Human Selenoprotein P PromoterSemantic proximity Read ↗

Human cDNA Encoding a Novel TGF- Superfamily Protein Highly Expressed in PlacentaSemantic proximity Read ↗

Organization of the human PTK7 gene encoding a receptor protein tyrosine kinase-like molecule and alternative splicing of its mRNASemantic proximity Read ↗

Structural organization of the gene encoding the rat pancreatitis-associated protein. Analysis of its evolutionary history reveals an ancient divergence from the other carbohydrate-recognition domain-containing genes.Semantic proximity Read ↗

p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I.Semantic proximity Read ↗

The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.