Effect of normal and immune sera on Haemophilus ducreyi 35000HP and its isogenic MOMP and LOS mutants.

doi:10.1006/mpat.1998.0250

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Article

Effect of normal and immune sera on Haemophilus ducreyi 35000HP and its isogenic MOMP and LOS mutants.

Microbial pathogenesis - 1 Feb 1999

Hiltke T J, Bauer M E, Klesney-Tait J, Hansen E J, Munson R S, Spinola S M

Abstract excerpt

A bactericidal assay was developed in order to test the effect of hyperimmune rabbit sera on the viability of serum-resistant Haemophilus ducreyi 35000HP. Testing of several lots of rabbit complement and time course experiments showed that the serum-sensitive H. ducreyi CIPA77 was killed efficiently by 25% complement at 35 degrees C in 3 h. We hypothesized that incubation of 35000HP under these conditions with...

Topics

Animals
Antibodies, Monoclonal
Antigens, Bacterial
Bacterial Outer Membrane Proteins
Blood Bactericidal Activity
Blotting, Western
Chancroid
Colony Count, Microbial
Complement System Proteins
Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Enzyme-Linked Immunosorbent Assay

Haemophilus ducreyi

Humans

Immunization

Lipopolysaccharides

Mutation

Rabbits

Source

Open in PubMed

Identifiers

PMID: 10090856
DOI: 10.1006/mpat.1998.0250

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