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Article

rpoB mutations in multidrug-resistant strains of Mycobacterium tuberculosis isolated in Italy.

Journal of clinical microbiology - 1 Apr 1999

Pozzi G, Meloni M, Iona E, Orrù G, Thoresen O F, Ricci M L, Oggioni M R, Fattorini L, Orefici G

Abstract excerpt

Mutations of rpoB associated with rifampin resistance were studied in 37 multidrug-resistant (MDR) clinical strains of Mycobacterium tuberculosis isolated in Italy. At least one mutated codon was found in each MDR strain. It was always a single-base substitution leading to an amino acid change. Nine different rpoB alleles, three of which had not been reported before, were found. The relative frequencies of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10074552
DOI: 10.1128/JCM.37.4.1197-1199.1999
PMCID: PMC88675

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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