Article
rpoB mutations in multidrug-resistant strains of Mycobacterium tuberculosis isolated in Italy.
Journal of clinical microbiology - 1 Apr 1999
Pozzi G, Meloni M, Iona E, Orrù G, Thoresen O F, Ricci M L, Oggioni M R, Fattorini L, Orefici G
Abstract excerpt
Mutations of rpoB associated with rifampin resistance were studied in 37 multidrug-resistant (MDR) clinical strains of Mycobacterium tuberculosis isolated in Italy. At least one mutated codon was found in each MDR strain. It was always a single-base substitution leading to an amino acid change. N...
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