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Article

Rapid hypothesis testing with Candida albicans through gene disruption with short homology regions.

Journal of bacteriology - 1 Mar 1999

Wilson R B, Davis D, Mitchell A P

Abstract excerpt

Disruption of newly identified genes in the pathogen Candida albicans is a vital step in determination of gene function. Several gene disruption methods described previously employ long regions of homology flanking a selectable marker. Here, we describe disruption of C. albicans genes with PCR products that have 50 to 60 bp of homology to a genomic sequence on each end of a selectable marker. We used the method...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10074081
DOI: 10.1128/JB.181.6.1868-1874.1999
PMCID: PMC93587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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