Article
Basic and clinical studies on ApoE gene typing by line probe assay (LiPA) as a biological marker for Alzheimer's disease and related disorders: multicenter study in Japan.
Methods and findings in experimental and clinical pharmacology - 1 Nov 1998
Nishimura T, Takeda M, Shinosaki K, Nishikawa T, Nakamura Y, Yoshida Y, Sasaki H, Arai H, Hirai S, Shouji M, Isse K, Tanaka K, Hamamoto M, Yamamoto H, Matsubayashi T, Nakashima K, Urakami K, Adachi Y, Nakamura S, Toji H, Yoshida H
Abstract excerpt
The fundamental reagent capability and clinical significance of ApoE gene typing has been investigated. The result of each test shows that the reagent capability satisfied the expected standard. Four-hundred thirty-nine samples classified into three groups (Alzheimer's disease (AD), other types of dementia and nondementia) were measured to examine the clinical significance. The rate of epsilon 4 genotype of each...
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