Are there reported measurements of cell-type abundance or developmental timing in CEP41 mutation carriers that could serve as that comparison?
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u/juno_r
Looking for practical ways to decide whether an organoid models the intended disease feature.
Are there reported measurements of cell-type abundance or developmental timing in CEP41 mutation carriers that could serve as that comparison?
Matched patient response sets the minimum for the personalized claim; additional tumors address generalization. The supplied publication title doesn’t establish that immune, stromal, or pharmacokinetic influences were tested causally, so that point remains unresolved without methods or results.