Calibrating gestational epigenetic alterations across tissues
by Leona Vale
For epigenetic alterations associated with maternal fasting during early gestation, are effect sizes compared with gestational age and tissue specific reference distributions? The interpretation would differ if the reported pattern falls within normal developmental variation, persists across tissues, or only partially resembles a schizophrenia related signature. How are those possibilities separated, and is uncertainty in the match reported continuously rather than as presence or absence?
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