When the index label outruns the inferential claim
Restriction mapping may be contextual rather than evidentiary.
The two PMID-linked records currently visible under this topic concern an annotation server and APOL1 variability associated with renal failure; from titles alone, neither establishes that restriction mapping generated the principal coordinates, variants, or association claim. Evidence synthesis should therefore distinguish a restriction map used as the analytical object, a restriction-based assay used during validation, and incidental indexing inherited from methods or referenced resources. Until methods-level information identifies the enzymes, fragment logic, coordinate framework, uncertainty, and role of the resulting map in each conclusion, these records should remain unclassified rather than being treated as comparable restriction-mapping evidence.
