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Gut metatranscriptome–virome profiling reveals active antimicrobial peptides (AMPs) encoded in plasmids and phages linked to human diseases

2025-07-25

Abstract excerpt

<title>Abstract</title> <p> Microbe-derived antimicrobial peptides (AMPs) play a crucial role in shaping the microbiota composition; however, their contribution to disease-associated dysbiosis remains poorly understood. Here, we assembled fecal metatranscriptomes from individuals with normal weight, obesity, and obesity plus metabolic syndrome, yielding 51,087 non-human transcripts. We screened 1,095 small open...

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Literature Corpus work
ffd07f4f-3c80-59ff-a81e-010693282761
DOI
10.21203/rs.3.rs-7160447/v1
Open publication

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