Article

Evaluating the potential neurotoxicity of hexanedione isomers: An in vitro approach

2008-01-01

Abstract excerpt

2,5-hexanedione (2,5HD) is the neurotoxic metabolite of the aliphatic hydrocarbon n-Hexane. The isomers, 2,3-hexanedione (2,3HD) and 3,4-hexanedione (3,4HD) are used as food additives. Although the neurotoxicity of 2,5HD is well established, there are no human data of the possible toxicity of the 2,3- and 3,4- isomers. MTT and flow cytometry were utilised to determine the cytotoxicity of hexanedione isomers in neu...

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Literature Corpus work: ff4a0f61-5143-55da-bf4b-8bba7c34dc4d
DOI: 10.48780/publications.aston.ac.uk.00012614

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