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Genome-wide analyses point to differences in genetic architecture of BMI between tall and short people

2020-09-25

Abstract excerpt

To examine differences in the genetic architecture of BMI between tall and short people, we conducted genome-wide and follow-up analyses using UK Biobank data. We identify 57 loci as height-specific, detect differences in SNP-based heritability between tall and short people and show how genetic correlations between the two rises during the lifespan. Using phenome-wide analyses (PHEWAS), a significant association b...

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Literature Corpus work
fcf4a62b-7844-5803-8929-f1d77017605a
DOI
10.1101/2020.09.24.312181
Open publication

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Genome-wide analyses point to differences in genetic architecture of BMI between tall and short peopleDOI 10.1101/2020.09.24.312181
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