Efficacy and safety of D-penicillamine, trientine and zinc in pediatric Wilson disease patients

Abstract excerpt

<title>Abstract</title> <p><bold>Objectives</bold> Wilson disease (WD) is a rare genetic disease affecting copper metabolism and the biliary tract’s copper excretion. Lifelong medication is necessary to prevent liver failure, neurological complications, and death. Although D-penicillamine (DPA), trientine, and zinc are used to treat Wilson disease (WD), there is limited research on the long-term outcomes of these...

Topics

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• Adenosine Triphosphatases
• Cation Transport Proteins
• Copper
• Copper-Transporting ATPases
• Hepatolenticular Degeneration
• Liver Diseases
• Mutation
• Nervous System Diseases

Identifiers and source

Literature Corpus work

f989d197-e259-5f96-9ab4-ef7380df3b75

DOI

10.21203/rs.3.rs-3470008/v1