Article

Comparative Analysis of Multimodal Large Language Models GPT-4o and o1 vs Clinicians in Clinical Case Challenge Questions

2025-06-23

Abstract excerpt

<h4>SUMMARY</h4> <h4>Background</h4> Generative Pre-trained Transformer 4 (GPT-4) has demonstrated strong performance in standardized medical examinations but has limitations in real-world clinical settings. The newly released multimodal GPT-4o model, which integrates text and image inputs to enhance diagnostic capabilities, and the multimodal o1 model, which incorporates advanced reasoning, may address these limi...

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Literature Corpus work: f92427a2-b159-5a3c-9b8a-91e566a5c9f8
DOI: 10.1101/2025.06.22.25330068

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