Article

Simplified Perioperative Serplulimab and Chemotherapy for Resectable Squamous NSCLC: a Phase II Trial with Biomarker Analysis

2026-01-22

Abstract excerpt

<h4>Purpose</h4> Squamous non-small cell lung cancer (sq-NSCLC) is a distinct subtype of NSCLC. This exploratory, phase II study investigated the feasibility and efficacy of a four-cycle perioperative regimen combining serplulimab with a taxane (paclitaxel or nab-paclitaxel) and carboplatin in patients with resectable stage II-IIIA sq-NSCLC. <h4>Methods</h4> This investigator-initiated, single-arm, phase II expl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f8ab9680-491d-54be-933b-8b38b85e9778
DOI: 10.64898/2026.01.20.26344483

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Simplified Perioperative Serplulimab and Chemotherapy for Resectable Squamous NSCLC: a Phase II Trial with Biomarker AnalysisDOI 10.64898/2026.01.20.26344483Read

Genomics of Squamous Cell Lung CancerSemantic proximity Read

Innovative Clinical Trials: The LUNG-MAP Study.Semantic proximity Read

Clinical, Pathologic, and Molecular Prognostic Factors in Patients with Early-Stage EGFR-Mutant NSCLC.Semantic proximity Read

Refining the treatment of NSCLC according to histological and molecular subtypesSemantic proximity Read

Clinicopathologic Features of Advanced Squamous NSCLC.Semantic proximity Read

Surgical results of the Lung Cancer Mutation Consortium 3 trial: A phase II multicenter single-arm study to investigate the efficacy and safety of atezolizumab as neoadjuvant therapy in patients with stages IB-select IIIB resectable non-small cell lung cancer.Semantic proximity Read

Targeted Therapy in Early Stage Non-small Cell Lung Cancer.Semantic proximity Read

Perioperative Therapy in Oncogene-Driven Non-Small Cell Lung Cancer: Current Strategies and Unanswered Questions.Semantic proximity Read

Efficacy and safety of different PD-1 inhibitors as first-line treatment for advanced or metastatic squamous non-small cell lung cancer: A retrospective real-world studySemantic proximity Read

Efficacy and safety of sintilimab in combination with chemotherapy in previously untreated advanced or metastatic nonsquamous or squamous NSCLC: two cohorts of an open-label, phase 1b study.Semantic proximity Read

Prognostic value of preoperative ctDNA and pathological venous invasion for recurrence in EGFR-mutated non-small cell lung cancer.Semantic proximity Read

The Adjuvant-Phase Dilemma After Neoadjuvant Chemoimmunotherapy in Resectable NSCLC: Evidence and Response-Guided StrategiesSemantic proximity Read