Host prior exposure augments heterogeneity in gene expression in both host and pathogen during <i>in vivo</i> infection

Abstract excerpt

Variability in acquired protection, whether from prior pathogen exposure or vaccination, is increasingly recognized as a key determinant of host population-level variation in disease traits. It remains unclear whether this extends to the within-host physiological environment and what the consequences are for reinfecting pathogens. Here, we asked whether prior pathogen exposure of hosts induces gene expression hete...

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• Anti-Inflammatory Agents, Non-Steroidal
• Aquaculture disease management and microbiota
• Bird Diseases
• Bird parasitology and diseases
• Herpesvirus Infections and Treatments
• Microbial infections and disease research
• Vector-borne infectious diseases
• Viral Infections and Vectors

Identifiers and source

Literature Corpus work

f840a291-e58c-55e3-ab00-5c46da10ea32

DOI

10.1101/2025.08.20.671316