Divergent porcine astrovirus 4: distinct respiratory and gastrointestinal clades with genetic differences

Abstract excerpt

In 2016, porcine astrovirus 4 (PoAstV4), historically associated with gastrointestinal infections, was first reported in piglets with acute respiratory disease in Oklahoma. Cases of PoAstV4 with consistent respiratory epitheliotropic viral lesions were later confirmed in 2023. Analyses of 38 new whole genomes indicate that respiratory-associated PoAstV4 strains are genetically distinct from those found associated...

Topics

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• Animal Virus Infections Studies
• Viral gastroenteritis research and epidemiology
• Viral Infections and Immunology Research

Identifiers and source

Literature Corpus work

f6c29934-1987-5de2-b79b-30ee209a7f41

DOI

10.1038/s44298-026-00218-0