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Proton-Pump Inhibitors in Eosinophilic Esophagitis: A Review Focused on the Role of Pharmacogenetics

2024-02-26

Abstract excerpt

Proton-pump inhibitors (PPIs) are the most administered first-line treatment for eosinophilic esophagitis (EoE). However, only around half of EoE patients respond histologically to PPI at double dosage. In addition, 70% of responders maintain EoE in remission after tapering the PPI dose. In order to avoid endoscopy with biopsies − the only accurate method of assessing PPI response − efforts have been made to ident...

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Literature Corpus work
f611fc40-bb97-5527-9384-f2cea844414c
DOI
10.20944/preprints202402.1496.v1
Open publication

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