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Article

Long-Term Loss of Response in Proton Pump Inhibitor-Responsive Esophageal Eosinophilia Is Uncommon and Influenced by CYP2C19 Genotype and Rhinoconjunctivitis.

The American journal of gastroenterology - 1 Nov 2015

Molina-Infante Javier, Rodriguez-Sanchez Joaquin, Martinek Jan, van Rhijn Bram D, Krajciova Jana, Rivas Maria D, Barrio Jesus, Moawad Fouad J, Martinez-Alcalá Carmen, Bredenoord Albert J, Zamorano Jose, Dellon Evan S

Abstract excerpt

OBJECTIVES: Proton pump inhibitor-responsive esophageal eosinophilia (PPI-REE) is diagnosed in at least one-third of patients with suspected eosinophilic esophagitis (EoE). We aimed to evaluate the durability and factors influencing long-term efficacy of PPI therapy. METHODS: Retrospective multicenter cohort study of patients with PPI-REE who had at least 12 months of follow-up. PPI therapy was tapered to the...

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PMID: 26416193
DOI: 10.1038/ajg.2015.314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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