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Unveiling an unexpected superoxide- mediated photooxidation mechanism of squalene monohydroperoxides to squalene hydroperoxy cyclic peroxides through ESR and LC-MS/MS analyses

2023-10-12

Abstract excerpt

Lipid cyclic peroxides are a rarely reported and documented class of compounds in the human organism. Recently, we reported the formation of squalene (SQ) hydroperoxy cyclic peroxides derived from SQ monohydroperoxide isomers (SQ-OOHs) for the first time. Notably, we successfully detected and quantified cis-2-OOH-3-(1,2-dioxane)-SQ in the human skin. Nevertheless, the underlying mechanism governing the formation o...

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Literature Corpus work
f5be17f3-d17d-54dc-97ea-8caafd4615f0
DOI
10.21203/rs.3.rs-3416184/v1
Open publication

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Unveiling an unexpected superoxide- mediated photooxidation mechanism of squalene monohydroperoxides to squalene hydroperoxy cyclic peroxides through ESR and LC-MS/MS analysesDOI 10.21203/rs.3.rs-3416184/v1
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