Article

Identification and Validation of a Four-Gene Prognostic Signature Based on PPAR Signaling Pathway for Oral Squamous Cell Carcinoma

2023-02-13

Abstract excerpt

This study aims to create a novel prognosis-related risk signature for oral squamous cell carcinoma (OSCC) based on the PPAR signaling pathway. TCGA and GEO data were respectively evaluated and verified. For the purpose of identifying OSCC prognostic genes, LASSO regression, univariate Cox, and multivariate Cox analyses were conducted. The predictive characteristic of OSCC was determined to be a combination of fou...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: f5a39258-bf0f-5739-a42d-d927b9b8c3c1
DOI: 10.21203/rs.3.rs-2560274/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification and Validation of a Four-Gene Prognostic Signature Based on PPAR Signaling Pathway for Oral Squamous Cell CarcinomaDOI 10.21203/rs.3.rs-2560274/v1Read

From survival rates to therapeutic targets: Investigating peroxisome-related genes in head and neck squamous cell carcinomaSemantic proximity Read

SPP1 and PLAU: two newly identified prognosis risk indicators in Oropharyngeal squamous cell carcinomaSemantic proximity Read

Construction and Validation of a Metabolic-Related Genes Prognostic Model for Oral Squamous Cell Carcinoma Based on BioinformaticsSemantic proximity Read

A Novel Pyroptosis-Related Gene Signature for Prognostic Prediction of Head and Neck Squamous Cell CarcinomaSemantic proximity Read

A Novel Pyroptosis-related Gene Signature for Prognostic Prediction of Head and Neck Squamous Cell CarcinomaSemantic proximity Read

A 3-mRNA-based prognostic signature of survival in oral squamous cell carcinomaSemantic proximity Read

A novel gene-based model for prognosis prediction of head and neck squamous cell carcinomaSemantic proximity Read

Identification of a six‐gene prognostic signature for oral squamous cell carcinomaSemantic proximity Read

Transcriptome and Mendelian randomization were combined to screen and validate prognostic genes associated with lipid autophagy in oral squamous cell carcinomaSemantic proximity Read

Bioinformatic analysis indicated that STARD4-AS1 might be a novel ferroptosis-related biomarker of oral squamous cell carcinomaSemantic proximity Read

A prognostic model for oral squamous cell carcinoma using 7 genes related to tumor mutational burdenSemantic proximity Read

Peroxisome proliferator-activated receptors signature reveal the head and neck squamous cell carcinoma energy metabolism phenotype and clinical outcome.Semantic proximity Read