Article

Temperate phage-antibiotic synergy is widespread, but varies by phage, host, and antibiotic pairing

2024-08-20

Abstract excerpt

With a decline in antibiotic effectiveness, there is a renewed interest in bacteriophage (phage) therapy. Phages are bacterial-specific viruses that can be used alone or with antibiotics to reduce bacterial load. Most phages are unsuitable for therapy because they are ‘temperate’ and can integrate into the host genome, forming a lysogen which is protected from subsequent phage infections. However, integrated phage...

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Literature Corpus work: f5552d2e-41af-5150-a891-94a16223d5e0
DOI: 10.1101/2024.08.20.608816

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