Article

Clonal hematopoiesis in individuals with <i>ANKRD26</i> or <i>ETV6</i> germline mutations

2021-11-22

Abstract excerpt

Currently, there are at least a dozen recognized hereditary hematopoietic malignancies (HHMs), some of which phenocopy others. Among these, three HHMs driven by germline mutations in ANKRD26, ETV6 , or RUNX1 share a phenotype of thrombocytopenia, qualitative platelet defects, and an increased lifetime risk of hematopoietic malignancies (HMs). Prior work has demonstrated that RUNX1 germline mutation carriers exp...

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Literature Corpus work: f4385db2-6151-59d7-9996-acc761a80ba1
DOI: 10.1101/2021.11.17.468983

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