Article

A five-dimensional functional state space for fingerprinting disease transcriptomes

2026-07-09

Abstract excerpt

High-throughput transcriptomics has transformed disease biology, but its outputs often remain fragmented into gene and pathway lists that are difficult to compare across conditions or use for human-AI interpretation. We developed a five-dimensional (5-D) functional state space that represents disease transcriptomes as coordinated activity patterns across major biological systems. The framework maps transcriptomic...

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Literature Corpus work: f3d2dfc6-9ca7-58e5-af6f-b56837f0f673
DOI: 10.64898/2026.07.04.736469

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