Article

IS <i>1216</i> drives the evolution of pRUM-like multidrug resistance plasmids in <i>Enterococcus faecium</i>

2025-07-15

Abstract excerpt

pRUM-like plasmids are commonly found in multidrug-resistant Enterococcus faecium , but the evolution of these plasmids has not been characterised in detail. When we analysed the genome sequences of two clinical E. faecium strains isolated in Birmingham, UK, we found two pRUM-like plasmids, pHHEf1 and pHHEf2. They were approximately 25 kb in size and shared the same 10 kb backbone, but contained starkly differen...

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Literature Corpus work: f388deac-baf1-574c-9c9c-dffe54cc5df9
DOI: 10.1101/2025.07.10.664085

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