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Proteomic Analysis of Aqueous Humor Reveals Changes in Extracellular Matrix Pathways in Proliferative Diabetic Retinopathy Patients Treated with Intravitreal Ranibizumab

2023-09-19

Abstract excerpt

Anti-VEGF therapy is commonly used to treat proliferative diabetic retinopathy (PDR), but the exact mechanism of VEGF signaling is not fully understood. Using data-independent acquisition mass spectrometry (DIA-MS), we analyzed proteomic changes in aqueous humor (AH) samples collected before and one week after intravitreal ranibizumab (IVR) treatment from 10 PDR patients to discover potential biomarkers. Resultant...

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Literature Corpus work: f27af8ba-2aee-547e-a48a-1c68fbe3b2a2
DOI: 10.22541/au.169513406.69458764/v1

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