Article

tiRNA-Val promotes angiogenesis via Sirt1–Hif-1α axis in mice with diabetic retinopathy

2021-09-30

Abstract excerpt

Diabetic retinopathy (DR) is a specific microvascular complication arising from diabetes, and its pathogenesis is notcompletely understood. tRNA-derived stress-induced RNAs (tiRNAs), a new type of small noncoding RNA generated by specific cleavage of tRNAs, has become a promising target forseveral diseases. However, the regulatory function of tiRNAs in DR and its detailed mechanism remain unknown. Here, we analyze...

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Literature Corpus work: f13430ee-e217-5b2b-92ce-d4fde2731ff9
DOI: 10.1101/2021.09.29.462300

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