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Parental Gut Microbiota Dysbiosis Drives Transgenerational DNA Methylation Transmission and Autism-like Behaviors in Offspring

2024-03-26

Abstract excerpt

<h4>Background: </h4> Autism spectrum disorder (ASD) presents a complex neurodevelopmental disorder whose origins remain elusive. Emerging research underscores the potential impact of parental environmental exposures on ASD risk in offspring. While the interplay between the "microbiota-gut-brain axis" and epigenetics is increasingly acknowledged in ASD pathogenesis, their comprehensive effects and regulatory mecha...

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Literature Corpus work
efee9cb5-d428-506c-9f43-d96c4603a348
DOI
10.21203/rs.3.rs-4131281/v1
Open publication

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Parental Gut Microbiota Dysbiosis Drives Transgenerational DNA Methylation Transmission and Autism-like Behaviors in OffspringDOI 10.21203/rs.3.rs-4131281/v1
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