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Methotrexate and Prednisolone compared to placebo and prednisolone in the treatment of Erythema Nodosum Leprosum - an international multicentre, double-blind randomised controlled clinical trial - MaPs in ENL

2026-05-21

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<h4>ABSTRACT</h4> <h4>Background</h4> Erythema nodosum leprosum (ENL) is a severe inflammatory complication of leprosy that often requires prolonged corticosteroid therapy which is associated with adverse effects. Methotrexate is an affordable immunomodulatory agent with limited evidence for its use in ENL treatment. We evaluated whether weekly oral methotrexate in additional to prednisolone reduces the need for...

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Literature Corpus work
eedd0244-6e4c-56d1-9d2b-1ae969d4c77a
DOI
10.64898/2026.05.19.26353561
Open publication

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Methotrexate and Prednisolone compared to placebo and prednisolone in the treatment of Erythema Nodosum Leprosum - an international multicentre, double-blind randomised controlled clinical trial - MaPs in ENLDOI 10.64898/2026.05.19.26353561
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