Article

Cytotoxic Potentials of Preserved and Preservative-free Brimonidine in Corneal Epithelial Cell Line

2022-04-18

Abstract excerpt

<h4>Purpose: </h4> This study aims to compare the cytotoxic, apoptotic, and oxidative effects of preserved and preservative-free forms of brimonidine 0.15% on the human corneal epithelial cell (HCEC) line. <h4>Methods: </h4>: Time-dependent cytotoxicity studies were performed at 5 and 15 minute and 1, 6, and 24 hour with the Alamar Blue method in HCEC treated with test solutions. For apoptotic studies, Annexin-V a...

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Literature Corpus work: ee3b655d-defe-5fb0-a0bd-9d649fb50214
DOI: 10.21203/rs.3.rs-1549484/v1

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