Article

The Cardiac Calcium Handling Machinery is Remodeled in Friedreich’s Ataxia

2023-11-13

Abstract excerpt

<h4>Background</h4> Friedreich’s ataxia (FA) is an inherited neurodegenerative disorder that causes progressive nervous system damage resulting in impaired muscle coordination. FA is the most common autosomal recessive form of ataxia and is caused by an expansion of the DNA triplet guanine–adenine–adenine (GAA) in the first intron of the Frataxin gene (FXN), located on chromosome 9q13. In the unaffected populatio...

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Literature Corpus work: ed8234af-0384-57ab-9a22-4757d841a9a1
DOI: 10.1101/2023.11.09.566141

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