Unravelling the Impact of miR-21 Overexpression on the MicroRNA Network and Cancer Pathways

Abstract excerpt

<h4> Abstract </h4> MicroRNAs (miRNA, miRs) are small noncoding RNAs that are ubiquitously expressed in all mammalian cells. Their primary function is the regulation of nascent RNA transcripts by direct binding to regions on the target. There is now exciting data to suggest that these miRNAs can bind to other miRNAs, and this may have a broader impact on gene regulation in disease states. The oncomiR miR-21 is o...

Topics

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• Caenorhabditis elegans
• Drosophila
• Gene Expression Profiling
• Germ-Line Mutation
• MicroRNAs
• Neoplasms
• Oncogenes
• RNA, Neoplasm

Identifiers and source

Literature Corpus work

ec659668-4bce-5574-bcbf-429deb295c15

DOI

10.1101/2024.05.10.593469