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TMEM45A Mediates Gastric Cancer Progression Through the P4HA1/Succinate/TGF-β Pathway

2026-07-15

Abstract excerpt

<title>Abstract</title> <p>Background Gastric cancer (GC) generally presents with poor prognosis owing to late diagnosis. Transmembrane protein 45A (TMEM45A) is involved in the progression of various tumors, yet its function and molecular mechanism in GC remain unclear. Methods We screened candidate genes via public bioinformatics databases, validated TMEM45A expression by immunohistochemistry in 75 paired GC t...

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Literature Corpus work
eb241cc3-8ec4-57b6-a58a-906a5c55c7da
DOI
10.21203/rs.3.rs-10246017/v1
Open publication

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