Article

Abdominal symptoms of invasive meningococcal disease are associated with the induction of plasminogen activator inhibitor in omental adipocytes

2025-02-26

Abstract excerpt

Abdominal symptoms are increasingly reported in invasive meningococcal disease (IMD), but the underlying mechanisms remain unclear. We aimed to explore the pathophysiology of these presentations using an animal model. We utilized a collection of 20 meningococcal isolates that were either associated or not associated with abdominal presentations, which were injected intraperitoneally into transgenic mice expressing...

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Literature Corpus work: ea0015f7-26f2-5d76-a97e-0fb04ed5d0ba
DOI: 10.1101/2025.02.26.640293

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