Article

Adaptive Sentinel Sampling for Founder-Enriched Populations: Quantifying the Resolution Gap in National Genome Programmes and Implications for Genomic Equity

2026-06-18

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> India harbours one of the world's most diverse mosaic of founder-enriched, endogamous communities, each shaped by centuries of genetic isolation and severe demographic bottlenecks. The Genome India Project (GIP), a landmark national genome programme, incorporates broadly similar per-population sampling targets across multiple strata. We hypothesised that this...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e90eb461-6e78-5104-9beb-e314898c1256
DOI: 10.21203/rs.3.rs-10009226/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Adaptive Sentinel Sampling for Founder-Enriched Populations: Quantifying the Resolution Gap in National Genome Programmes and Implications for Genomic EquityDOI 10.21203/rs.3.rs-10009226/v1Read

50,000 years of evolutionary history of India: Impact on health and disease variationSemantic proximity Read

Fine-scale genetic structure and population-specific clinically relevant variants in the indigenous tribal populations of IndiaSemantic proximity Read

An Atlas of Indian Genetic DiversitySemantic proximity Read

Reconstructing Indian population history.Semantic proximity Read

Unraveling the propensity of various genetic disorders and syndromes in the Koraga, an aboriginal tribe from southern India.Semantic proximity Read

Population-Scale Landscape of Mobile Element Insertions Across 82 Diverse Indian PopulationsSemantic proximity Read

The story of the lost twins: decoding the genetic identities of the Kumhar and Kurcha populations from the Indian subcontinent.Semantic proximity Read

Unity in diversity: an overview of the genomic anthropology of India.Semantic proximity Read

A rare splice-site variant in cardiac troponin-T (<i>TNNT2)</i>: The need for ancestral diversity in genomic reference datasetsSemantic proximity Read

Reinfection or reactivation: Genome-based two distinct SNP profile of SARS-CoV2 repositivity in an Indian case.Semantic proximity Read

Most disease gene variants show minimal population differentiation despite incomplete coverageSemantic proximity Read

Layers in the sand: The genetic imprint of migration, culture, and Indus craft in the Thar desertSemantic proximity Read