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Article

Effect of Losartan on Symptomatic Outpatients with COVID-19: A Randomized Clinical Trial

2021-02-17

Abstract excerpt

Background: The SARS-CoV-2 virus enters cells via the ACE2 receptor, disrupting the renin-angiotensin-aldosterone axis, potentially contributing to lung injury. Treatment with angiotensin receptor blockers(ARBs) may mitigate these effects, though induction of ACE2 expression could increase viral entry, replication, and worsen disease.<br><br>Methods: This study represents a placebo-controlled blinded randomized cl...

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Literature Corpus work
e8b622cf-18e4-5d83-b401-a222f99337f3
DOI
10.2139/ssrn.3787463
Open publication

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Effect of Losartan on Symptomatic Outpatients with COVID-19: A Randomized Clinical TrialDOI 10.2139/ssrn.3787463
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