Article

Characterization of plasma circulating small extracellular vesicles in patients with metastatic solid tumors and newly diagnosed brain metastasis

2021-11-19

Abstract excerpt

<h4>Purpose</h4> Nearly 40% of the advanced cancer patients will present brain metastases during the course of their disease, with a 2-year life expectancy of less than 10%. Immune system impairment, including the modulation of both STAT3 and PD-L1, is one of the hallmarks of brain metastases. Liquid biopsy could offer several advantages in brain metastases management, such as the possibility of non-invasive dyna...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e876646d-367c-5a92-920d-d552f75015f4
DOI: 10.1101/2021.11.18.469115

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterization of plasma circulating small extracellular vesicles in patients with metastatic solid tumors and newly diagnosed brain metastasisDOI 10.1101/2021.11.18.469115Read

Circulating extracellular vesicle-based multianalyte biomarker signatures accurately distinguish glioblastoma from brain metastasis patients before surgerySemantic proximity Read

Decoding Brain Metastasis With Liquid Biopsy: Biomarkers and Technologies in EGFR-Mutant NSCLC.Semantic proximity Read

Microvesicles in Cancer: Small Size, Large PotentialSemantic proximity Read

Diagnostic and Therapeutic Potential of Extracellular Vesicles in B-Cell MalignanciesSemantic proximity Read

Extracellular vesicles in hematological malignancies: EV-dence for reshaping the tumoral microenvironmentSemantic proximity Read

Recent advances of small extracellular vesicle biomarkers in breast cancer diagnosis and prognosisSemantic proximity Read

A novel microRNA signature for the detection of melanoma by liquid biopsySemantic proximity Read

Unraveling the Enigma of Melanoma Brain Metastasis: New Horizons in Mechanisms, Diagnosis, and TherapySemantic proximity Read

Clinical relevance of extracellular vesicles in hematological neoplasms: from liquid biopsy to cell biopsy.Semantic proximity Read

Monitoring of single extracellular vesicle heterogeneity in cancer progression and therapySemantic proximity Read

Extracellular vesicles and particles as mediators of long-range communication in cancer: connecting biological function to clinical applicationsSemantic proximity Read

Liquid Biopsy in Melanoma: Significance in Diagnostics, Prediction and Treatment Monitoring.Semantic proximity Read