Article

The <i>Drosophila</i> SPECC1L homolog, Split Discs, co-localizes with non-muscle myosin II and regulates focal adhesion dynamics

2025-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Allelic variations of Sperm antigen with calponin homology and Coiled-Coil domains 1 Like (SPECC1L) have been associated with a spectrum of cranial-facial pathologies including Teebi hypertelorism and Opitz G/BBB syndrome which manifest as clefting of the palate, wide-eyes, and incomplete closure of the esophagus among others. These pathologies may be indicative of improper cranial neural crest...

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Literature Corpus work: e8142b25-d636-561d-a5a1-3efd5aa4491b
DOI: 10.1101/2025.04.06.647460

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