Article

Noninvasive Prenatal Testing for Fetal Trisomies in a Routinely Screened First-Trimester Population

2013-02-26

Abstract excerpt

Over the last 4 decades, screening and diagnosis of fetal aneuploidies have changed from second-trimester amniocentesis to first-trimester chorionic villous sampling (CVS) in high-risk women. Although testing with CVS or amniocentesis is diagnostic, both carry the risk of miscarriage. Noninvasive prenatal testing (NIPT) by analysis of cell-free DNA (cfDNA) in maternal blood has provided highly accurate detection o...

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Literature Corpus work: e8019428-4fc9-52ac-8909-90c1f2c469d6
DOI: 10.1097/ogx.0b013e318285bf66

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