Article

CUSP: Complex Spike Sorting from Multi-electrode Array Recordings with U-net Sequence-to-Sequence Prediction

2025-11-18

Abstract excerpt

<h4>Background</h4> Complex spikes (CSs) in cerebellar Purkinje cells convey unique signals complementary to Simple spike (SS) action potentials, but are infrequent and variable in waveform. Their variability and low spike counts, combined with recording artifacts such as electrode drift, make automated detection challenging. <h4>New Method</h4> We introduce CUSP (CS sorting via U-net Sequence Prediction), a ful...

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Literature Corpus work: e763a232-e2de-511b-895f-4ab67a427bc9
DOI: 10.1101/2025.11.18.689109

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