Article

Clinical and genetic study of twelve Chinese Han families with non-syndromic deafness

2019-11-25

Abstract excerpt

<title>Abstract</title> <p>BACKGROUND: Non-syndromic hearing loss is clinically and genetically heterogeneous. In this study, we characterized the clinical features of twelve Chinese Han deaf families in which mutations in common deafness genes GJB2 , SLC26A4 and MT-RNR1 were excluded. RESULTS: Targeted next-generation sequencing of 147 known deafness genes was performed in probands of ten families, while whole-e...

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Literature Corpus work: e6262d81-26cf-5b51-98b8-3ab6d23e1488
DOI: 10.21203/rs.2.17760/v1

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