Article

Development of VHH antibodies specific to cucurbit chlorotic yellows virus using an alpaca naïve cDNA library

2022-09-01

Abstract excerpt

Variable domain of heavy chain of heavy-chain (VHH) antibodies (Abs) have been widely applied for the detection and therapeutics of viral pathogens. Here, we report the development of VHH-derived Abs specific to cucurbit chlorotic yellows virus (CCYV) via screening of an alpaca naïve VHH gene library. The screened VHH Ab was expressed as a fusion protein with the Fc fragment of mouse immunoglobulin G, and its reac...

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Literature Corpus work: e4c849cd-023b-5e53-a5c2-3f3eae274120
DOI: 10.1007/s10327-022-01076-3

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