Article

Circulating miR-4532 is associated with loss of ambulation in dysferlinopathy

2026-01-06

Abstract excerpt

<h4>Background</h4> Limb-girdle muscular dystrophies (LGMDs) are inherited myopathies characterized mainly by progressive weakness of the proximal muscles of the shoulder and pelvic girdle areas, leading to functional decline and eventual loss of independent ambulation. Dysferlinopathy (LGMD2B) is an autosomal recessive LGMD subtype, is caused by mutations in the DYSF gene that lead to lack of dysferlin which re...

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Literature Corpus work: e2dbc39f-096d-56ea-a654-032a5cac004d
DOI: 10.64898/2026.01.05.697793

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