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Opioid-Free Versus Opioid-Based Anesthesia in Laparoscopic Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2025-09-11

Abstract excerpt

<h4>Background: </h4> Opioid-based anesthesia (OBA) has traditionally been the standard approach for intraoperative analgesia, but its use is associated with adverse effects such as respiratory depression, nausea and vomiting, hyperalgesia, and delayed recovery. To mitigate these issues, opioid-free anesthesia (OFA) regimens combining non-opioid agents (e.g., dexmedetomidine, ketamine, lidocaine, magnesium, esmolo...

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Literature Corpus work
e1ce30bf-4bcf-53e3-afe7-83e35e16fc68
DOI
10.20944/preprints202509.0915.v1
Open publication

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Opioid-Free Versus Opioid-Based Anesthesia in Laparoscopic Surgery: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsDOI 10.20944/preprints202509.0915.v1
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