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A Novel Linear Displacement Isothermal Amplification with Strand Displacement Probes (LDIA-SD) in a Pocket-Size Device for Point-of-Care Testing Of Infectious Diseases

2022-10-28

Abstract excerpt

Nucleic acid amplification is crucial for disease diagnosis, especially lethal infectious diseases such as COVID-19. Compared with PCR, isothermal amplification methods are advantageous for point-of-care testing (POCT). However, complicated primer design limits their application in detecting some short targets or sequences with abnormal GC content. Herein, we developed a novel linear displacement isothermal amplif...

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Literature Corpus work: e1b3501f-be2e-5ed7-8088-f03f324aab09
DOI: 10.2139/ssrn.4246794

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